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Motor Neurone Disease: Research

Question for Department for Business, Energy and Industrial Strategy

UIN 135876, tabled on 11 January 2021

To ask the Secretary of State for Business, Energy and Industrial Strategy, pursuant to the Answer of 11 January to Question 130668, if he will name the projects that received funding in 2019-20 from the (a) Medical Research Council and (b) National Institute for Health Research.

Answered on

14 January 2021

The Medical Research Council (MRC) funded seven Motor Neurone Disease-related projects in 2019-20 in pursuant to the Answer of 11 January to Question 130668. Details of the projects can be found in the table below.

Research Organisation

Project Title

Start Date

End Date

Amount Awarded (£m)

University College London

The impact of TDP-43 on translation and the response to axonal damage in amyotrophic lateral sclerosis




University College London

Elucidating early stage ALS pathomecanisms that drive mitochondrial dysfunction




University of Sheffield

Regulation of ER-mitochondria contacts in neurodegeneration




University College London

A 5 year prospective follow-up clinical and imaging investigation of demyelinating clinically isolated syndrome (CIS)




Imperial College London

Regulated proteolysis of p62/SQSTM1, nutrient-sensing and human disease




University of Edinburgh

Investigating the molecular mechanisms of mutant C9orf72 human iPSC-derived astrocyte-mediated motor neuron deficits




Newcastle University

Novel MRI Biomarkers in Neuromuscular Disease




The National Institute for Health Research (NIHR) funded no Motor Neurone Disease-related projects during this period.

Further details of all projects funded by UK Research and Innovation (UKRI), which MRC has been integrated into, can be found at

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