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Medical Treatments: Research

Question for Department of Health and Social Care

UIN HL8776, tabled on 5 October 2020

To ask Her Majesty's Government what assessment they have made of the research published in the Journal of Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases, Infections, Genetics and Evolution, A survey of genetic variants in SARS-CoV-2 interacting domains of ACE2, TMPRSS2 and TLR3/7/8 across populations, published on 26 August.

Answered on

20 October 2020

The Government recognises the need to research how genomic variants may impact COVID-19 severity. Genomics England has partnered with the University of Edinburgh Genetics of Mortality in Critical Care study and Illumina to deliver an ambitious programme of whole genome sequencing (WGS) to determine genomic factors influencing the severity of response to COVID-19, who responds best to which treatments, and to inform the development of novel therapies and vaccines. The study aims to perform WGS of up to 20,000 patients severely affected by COVID-19 and a matched control group of up to 15,000 with an asymptomatic or mild response to COVID-19.